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The number of global coronavirus cases surged past 300,000 on Sunday, with more than 13,000 deaths worldwide, according to John Hopkins University, which reported that China, Italy and the U.S. had the most people diagnosed with the respiratory illness.

The news came as the number of Americans under virtual lockdown grew to over 80 million on Saturday, and Ohio issued new shelter-in-place orders.

German Chancellor Angela Merkel is herself in quarantine after a doctor who treated her tested positive for coronavirus, her press office announced Sunday.

And Sen. Rand Paul became the first known U.S. Senator to test positive for coronavirus.

“He is feeling fine and is in quarantine. He is asymptomatic and was tested out of an abundance of caution due to his extensive travel and events,“ the senator’s Twitter account said on Sunday.

Elsewhere, China ended a three-day streak of reporting no new coronavirus cases after 46 people tested positive for COVID-19. On the same day, China\'s National Health Commission also reported six new deaths. Five of the deaths occurred in Wuhan in Hubei province, where the outbreak originated late last year.

From citywide quarantines to infections aboard cruise ships to cancellations of major international events, the global public health emergency caused by the coronavirus has been unfolding rapidly and dramatically. The virus, which causes a disease known as COVID-19, emerged in Wuhan, China, late last year, but it has since spread to at least 110 countries.