What medications interact with Poxet 90 Mg?

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    stephenbarkin74 April 25, 2024 7:02 AM EDT 0 likes

    Poxet 90 mg contains dapoxetine as its active ingredient and is primarily used to treat premature ejaculation (PE) in men. When considering medications that may interact with Poxet 90 mg, it's important to understand potential drug interactions that could affect its safety and effectiveness. Here are some medications that may interact with Poxet 90 mg:

    1. Other Serotonin Reuptake Inhibitors (SSRIs) or Antidepressants: Poxet 90 mg is itself an SSRI and is used off-label to treat PE. Concurrent use of Poxet 90 mg with other SSRIs or antidepressants can increase the risk of serotonin syndrome, a potentially life-threatening condition characterized by symptoms such as confusion, hallucinations, rapid heartbeat, sweating, shivering, tremors, muscle stiffness, and gastrointestinal issues.

    2. Monoamine Oxidase Inhibitors (MAOIs): MAOIs are a class of antidepressant medications that can interact with Poxet 90 mg and increase the risk of serotonin syndrome. MAOIs should be discontinued at least 14 days before starting Poxet 90 mg to avoid this interaction.

    3. Thioridazine and Other Antipsychotic Medications: Thioridazine and certain other antipsychotic medications can prolong the QT interval, a measure of the heart's electrical activity. Concurrent use of these medications with Poxet 90 mg may increase the risk of QT interval prolongation and potentially life-threatening arrhythmias.

    4. Certain Antifungal Medications: Some antifungal medications, such as ketoconazole and itraconazole, can inhibit the metabolism of Poxet 90 mg, leading to increased blood levels of dapoxetine and an increased risk of side effects.

    5. HIV/AIDS Medications: Certain medications used to treat HIV/AIDS, such as ritonavir, can inhibit the metabolism of Poxet 90 mg and increase blood levels of dapoxetine. This can increase the risk of side effects associated with Poxet 90 mg.

    6. Nitrates and Nitric Oxide Donors: Poxet 90 mg should not be used concurrently with nitrates or nitric oxide donors (such as amyl nitrite or nitroglycerin) as this combination can cause a sudden and severe decrease in blood pressure, leading to fainting, dizziness, or even a heart attack or stroke.

    These are just a few examples of medications that may interact with Poxet 90 mg. It's important to consult with a healthcare provider or pharmacist before starting Poxet 90 mg to ensure its safety and to discuss any potential drug interactions based on your individual medical history and current medications.