Does Imatinib Affect The Kidneys?

Imatinib 400mg Tablet also known as Gleevac is used in the treatment of leukemia. It is a tyrosine kinase inhibitor that inhibits the functioning of BCR-ABL tyrosine kinase which causes white blood cell proliferation. As a result, it inhibits the signals that cause cell proliferation. Imatinib is taken as an oral tablet once or twice as prescribed by the doctor.

Does Imatinib affect kidneys –

Studies have reported that the risk of getting a kidney disorder is higher in patients undergoing imatinib treatment than in others. Regular use of Imatinib Tablets weakens the functioning of the kidneys.

Some other side effects of Imatinib are –

• Diarrhea, vomiting, nausea
• Sudden weight loss
• Loss of appetite, dizziness, and also confusion
• Blurred vision and pink eye
• Redness, rashes of skin, also swelling of joints
• Trouble in sleeping
• Hair loss
• Shortness of breath
• Yellowing of eye and skin
• Coughing up pink mucous
• Irregular heart rate and also chest pain

Some of the precautions related to imatinib are –

• Some of the ingredients of imatinib can cause an allergic reaction. Therefore, it is advisable to get complete information about the drug and consult the doctor for the same. Redness, rashes, and hives are some of the initial symptoms of an allergy.
• Inform your doctor regarding past medical conditions related to heart liver kidney and thyroid.
• Imatinib is taken orally with or without meal. However, it is advisable to avoid grapefruit and grapefruit juice while taking this medicine.
• Avoid driving and using heavy machinery as imatinib can cause dizziness as a side effect.
• Avoid pregnancy and breastfeeding as imatinib can cause fetal harm. It is advisable to avoid pregnancy during and till 2 weeks after the last dosage.
• Imatinib can interact with several other medications like – acetominphen, fentora, indinavir, rifabutin, fentanyl, and even blood thinners like warfarin.

Conclusion –

Imatinib 400mg tablets is an effective cure for several types of leukemia. Hence, they can be purchased from Magicine Pharma with ease.

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